Per suggestion from @jeffpaul

class-two-factor-core.php

@@ -1885,7 +1885,7 @@ public static function user_two_factor_options( $user ) {
 							</option>
 						<?php endforeach; ?>
 					</select>
-					<p class="description"><?php esc_html_e( 'Select the primary method used during the login by default.', 'two-factor' ) ?></p>
+					<p class="description"><?php esc_html_e( 'Select the primary method to use for two-factor authentication when signing into this site.', 'two-factor' ) ?></p>
 				</td>
 			</tr>
 			</tbody>