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Exploring the Efficacy of Psychological Treatments for Depression: A Multiverse Meta-Analysis

This repository contains the data, code, and resources used for the publication "Exploring the efficacy of psychological treatments for depression: a multiverse meta-analysis protocol", available at BMJ Open.

Repository Structure

Files and Folders

  • data/
    Contains the datasets used for the analysis, formatted for the R Markdown files.

  • multiverse_1_data-cleaning.Rmd
    Prepares and cleans the data for use in the multiverse analysis.

  • multiverse_2_multiverse-analysis.Rmd
    Conducts the multiverse meta-analysis by systematically exploring variations in analytical choices.

  • multiverse_3_descriptive-specification-plot.Rmd
    Generates descriptive plots summarizing the specifications used in the multiverse.

  • multiverse_4_inferential-specification-plot.Rmd
    Produces inferential specification plots to visualize variability in the results across analytical choices.

  • multiverse_4_inferential-specification-plot_cre_avg.Rmd
    Generates additional inferential plots focusing on conditional response effect averages.

  • multiverse_5_GOSH-plot.Rmd
    Creates a GOSH (Graphical Overview for Study Heterogeneity) plot to investigate the robustness of findings.

  • multiverse_6_results.Rmd
    Summarizes the main results from the multiverse meta-analysis, including tables and visualizations.

How to Use

  1. Download this repository as a ZIP file by clicking the green "Code" button at the top of the GitHub page and selecting "Download ZIP".
  2. Extract the contents of the ZIP file to a folder on your computer.
  3. Open and execute the R Markdown files in RStudio in the following order:
    • multiverse_1_data-cleaning.Rmd
    • multiverse_2_multiverse-analysis.Rmd
    • Follow with the remaining files sequentially to replicate the entire analysis pipeline.

Citation

If you use the code or data in this repository, please cite the publication:

Exploring the efficacy of psychological treatments for depression: a multiverse meta-analysis protocol
Constantin Yves Plessen, Eirini Karyotaki, Pim Cuijpers
Published in BMJ Open.
DOI: 10.1136/bmjopen-2021-050197.

Contact

For questions or feedback about this repository, please contact Constantin Yves Plessen at yves [dot] plessen [at] gmail [dot] com