diff --git a/.changeset/tender-nails-tickle.md b/.changeset/tender-nails-tickle.md
new file mode 100644
index 000000000000..42ee87bd3528
--- /dev/null
+++ b/.changeset/tender-nails-tickle.md
@@ -0,0 +1,7 @@
+---
+"miniflare": patch
+---
+
+fix: ensure IPv6 addresses can be used as `host`s
+
+Previously, if Miniflare was configured to start on an IPv6 `host`, it could crash. This change ensures IPv6 addresses are handled correctly. This also fixes `wrangler dev` when using IPv6 addresses such as `::1` with the `--ip` flag.
diff --git a/packages/miniflare/src/index.ts b/packages/miniflare/src/index.ts
index c2a711902cd9..ea06da2aa531 100644
--- a/packages/miniflare/src/index.ts
+++ b/packages/miniflare/src/index.ts
@@ -997,7 +997,7 @@ export class Miniflare {
 			requestedPort = this.#socketPorts?.get(id);
 		}
 		// Otherwise, default to a new random port
-		return `${host}:${requestedPort ?? 0}`;
+		return `${getURLSafeHost(host)}:${requestedPort ?? 0}`;
 	}
 
 	async #assembleConfig(loopbackPort: number): Promise<Config> {
diff --git a/packages/miniflare/test/index.spec.ts b/packages/miniflare/test/index.spec.ts
index dbc4fb0b4c9a..c1788b1a3001 100644
--- a/packages/miniflare/test/index.spec.ts
+++ b/packages/miniflare/test/index.spec.ts
@@ -213,6 +213,21 @@ const localInterface = (interfaces["en0"] ?? interfaces["eth0"])?.find(
 		t.is(await res.text(), "body");
 	}
 );
+test("Miniflare: can use IPv6 loopback as host", async (t) => {
+	const mf = new Miniflare({
+		host: "::1",
+		modules: true,
+		script: `export default { fetch() { return new Response("body"); } }`,
+	});
+	t.teardown(() => mf.dispose());
+
+	let res = await mf.dispatchFetch("https://example.com");
+	t.is(await res.text(), "body");
+
+	const worker = await mf.getWorker();
+	res = await worker.fetch("https://example.com");
+	t.is(await res.text(), "body");
+});
 
 test("Miniflare: routes to multiple workers with fallback", async (t) => {
 	const opts: MiniflareOptions = {