Skip to content
New issue

Have a question about this project? Sign up for a free GitHub account to open an issue and contact its maintainers and the community.

By clicking “Sign up for GitHub”, you agree to our terms of service and privacy statement. We’ll occasionally send you account related emails.

Already on GitHub? Sign in to your account

Feature Request: Duphold Stats for Insertions #42

Open
jjfarrell opened this issue Mar 17, 2021 · 2 comments
Open

Feature Request: Duphold Stats for Insertions #42

jjfarrell opened this issue Mar 17, 2021 · 2 comments

Comments

@jjfarrell
Copy link

It would be great that the Duphold stats be extended to insertions such as those generated by Manta. Duphold has been great for the QC of DEL and DUP FP variants.

@brentp
Copy link
Owner

brentp commented Mar 17, 2021

what would be reported for insertions? duphold is mostly depth-based, but it could potentially extract other information.

@jjfarrell
Copy link
Author

Here is one approach I think might work-At the insertion sites, the cigar should have an "I" in the read. So the depth of the insertion would be the number of reads with an "I" in the cigar string of the read at the insert site.

Sign up for free to join this conversation on GitHub. Already have an account? Sign in to comment
Labels
None yet
Projects
None yet
Development

No branches or pull requests

2 participants