08-Group-Sequential-Designs.Rmd

# Group Sequential Designs {#groupsequential}

https://rinpharma.shinyapps.io/gsdesign/
https://arxiv.org/pdf/2303.01040.pdf
https://www.rpact.org/vignettes/planning/rpact_boundary_examples/
gsDesign



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## Group Sequential Designs




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## Power & Sample Size Calculations




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## Analyses: Unadjusted and Adjusted